This study centred on mentoring for enhanced employment and employability in library and information science (LIS) education in Nigeria. Descriptive Survey research design was adopted for the investigation. A population of hundred (100) respondents were selected while the sample of fifty (50) respondents made up of librarians in John Harris library responded to the questions. Relevant data were collected from the sample through personal contact method of administration of mentoring for enhanced employment and employability in library and information science (LIS) education Questionnaires (MFEEELISQ). The data collected were presented in Tables and analyzed using simple percentages. The findings from data analyzed include that participation in professional association, provision of sponsorship for conferences, seminar are some of the programmes through which librarians are mentored; enhancement for job employment and employability, improvement of team work and cooperation in the working environment are some of the benefits of mentoring in LIS. The challenges to effective mentoring among librarians include unconstructive criticism by the mentor to the mentee, broken confidentiality by both the mentor and the mentee, absence of mentoring orientation in librarianship and some suggested ways to overcome challenges to effective mentoring. Based on the findings, it is recommended that willingness of the mentor and the mentee to listen and learn from each other is important as well as adequate training should be organized for both mentors and mentees.